DNMT3A 抗体
Quick Overview for DNMT3A 抗体 (ABIN6943093)
抗原
See all DNMT3A 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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纯化方法
- Affinity purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300.
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免疫原
- Polyclonal antibody raised in rabbit against human DNMT3A, (DNA methyltransferase 3A), using a KLH-conjugated synthetic peptide corresponding to amino acids 44-58
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anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 500-700) antibody
DNMT3A 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 457-486) antibodyDNMT3A 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB01852 unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 26-100) antibodyDNMT3A 适用: 人, 小鼠, 大鼠 FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 46-180) antibodyDNMT3A 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 4G5F11 unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (2meLys44) antibodyDNMT3A 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 457-486) antibodyDNMT3A 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 1-912) antibodyDNMT3A 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 680-902) antibodyDNMT3A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 1-912) antibodyDNMT3A 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 705-908), (C-Term) antibodyDNMT3A 适用: 人, 小鼠 WB, IHC, ICC, ChIP 宿主: 小鼠 Monoclonal 64B1446 unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IP(1-2 μg)
ChIP-seq() -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.75 μg/μL
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缓冲液
- PBS with 0.05 % sodium azide and 0.05 % Proclin300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))
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别名
- DNMT3A
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背景
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Synonyms: DNMT3A2, TBRS
Background: Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells. Acts as a transcriptional corepressor for ZBTB18. Recruited to trimethylated 'Lys-36' of histone H3 (H3K36me3) sites. Can actively repress transcription through the recruitment of HDAC activity.
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基因ID
- 1788
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UniProt
- Q9Y6K1
抗原
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