Recombinant DLG2 抗体 (AA 600-870)
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Quick Overview for Recombinant DLG2 抗体 (AA 600-870) (ABIN6943005)
抗原
See all DLG2 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 600-870
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原理
- PSD93/DLG2 Recombinant Antibody
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交叉反应
- 人
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预测反应
- Mouse,Rat
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纯化方法
- Purified by Protein A.
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免疫原
- Recombinant protein within human PSD93 aa 600-870
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亚型
- IgG
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应用备注
- WB(1:1000-5000), FCM(1 μg/Test), IHC-P(1:200-400)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- DLG2 (Discs, Large Homolog 2 (DLG2))
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别名
- DLG2
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背景
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Synonyms: Disks large homolog 2, Channel-associated protein of synapse-110, Postsynaptic density protein PSD-93, Chapsyn-110, DLG2, discs large MAGUK scaffold protein 2, PSD93, PPP1R58,
Background: This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. The encoded protein forms a heterodimer with a related family member that may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described, but their full-length nature is not known. DLG2 is required for the perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in the regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses.
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基因ID
- 1740
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UniProt
- Q15700
抗原
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