CUBN 抗体
-
- 抗原 See all CUBN 抗体
- CUBN (Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN))
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 单克隆
-
标记
- This CUBN antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人
- 纯化方法
- Purified by Protein A.
- 免疫原
- Recombinant protein within C-terminal human Cubilin
- 克隆位点
- 7B12
- 亚型
- IgG
- Top Product
- Discover our top product CUBN Primary Antibody
-
anti-Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN) antibody
CUBN 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN) (AA 51-150) antibodyCUBN 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN) (AA 3157-3274) antibodyCUBN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN) (AA 3157-3274) antibodyCUBN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN) (N-Term) antibodyCUBN 适用: 人 WB, IHC, ICC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN) (AA 3511-3623) antibodyCUBN 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN) (AA 98-207) antibodyCUBN 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN) (AA 3511-3623) antibodyCUBN 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN) (AA 3157-3274) antibodyCUBN 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN) (AA 3511-3623) antibodyCUBN 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
WB 1:300-5000
IHC-P 1:200-400 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 12 months
-
- 抗原
- CUBN (Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN))
- 别名
- Cubilin (CUBN 产品)
- 别名
- GP280 antibody, IFCR antibody, MGA1 antibody, AA408369 antibody, AL022750 antibody, D2Wsu88e antibody, gp280 antibody, cubilin antibody, cubilin (intrinsic factor-cobalamin receptor) antibody, LOC411053 antibody, CUBN antibody, cubn antibody, Cubn antibody
- 背景
-
Synonyms: CUBN, 460 kDa receptor, Intestinal intrinsic factor receptor, Intrinsic factor-cobalamin receptor, Intrinsic factor-vitamin B12 receptor, IFCR
Background: Cotransporter which plays a role in lipoprotein, vitamin and iron metabolism, by facilitating their uptake. Binds to ALB, MB, Kappa and lambda-light chains, TF, hemoglobin, GC, SCGB1A1, APOA1, high density lipoprotein, and the GIF-cobalamin complex. The binding of all ligands requires calcium. Serves as important transporter in several absorptive epithelia, including intestine, renal proximal tubules and embryonic yolk sac. Interaction with LRP2 mediates its trafficking throughout vesicles and facilitates the uptake of specific ligands like GC, hemoglobin, ALB, TF and SCGB1A1. Interaction with AMN controls its trafficking to the plasma membrane and facilitates endocytosis of ligands. May play an important role in the development of the peri-implantation embryo through internalization of APOA1 and cholesterol. Binds to LGALS3 at the maternal-fetal interface.
- 基因ID
- 8029
- UniProt
- O60494
- 途径
- Metabolism of Steroid Hormones and Vitamin D, Lipid Metabolism
-
