CLOCK 抗体
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- 抗原 See all CLOCK 抗体
- CLOCK (Clock Homolog (Mouse) (CLOCK))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This CLOCK antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- Recombinant protein
- 克隆位点
- 3F9
- 亚型
- IgG
- Top Product
- Discover our top product CLOCK Primary Antibody
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- 应用备注
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- CLOCK (Clock Homolog (Mouse) (CLOCK))
- 别名
- CLOCK (CLOCK 产品)
- 别名
- CG7391 antibody, CLK antibody, CLOCK antibody, Dmel\\CG7391 antibody, Jerk antibody, Jrk antibody, PAS1 antibody, bHLHe10 antibody, clk antibody, clock antibody, dCLK antibody, dCLK/JRK antibody, dCLOCK antibody, dClck antibody, dClk antibody, dClock antibody, dclk antibody, jrk antibody, Xclk antibody, XClock antibody, zCLOCK1 antibody, zfCLOCK1 antibody, 5330400M04Rik antibody, KAT13D antibody, bHLHe8 antibody, mKIAA0334 antibody, Clock antibody, clock circadian regulator antibody, clock homolog (mouse) antibody, clock circadian regulator a antibody, circadian locomotor output cycles kaput antibody, clock circadian regulator L homeolog antibody, Clk antibody, CLOCK antibody, clock antibody, clocka antibody, Clock antibody, clock.L antibody
- 背景
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Synonyms: Circadian locomoter output cycles protein kaput, Class E basic helix-loop-helix protein 8, hCLOCK, bHLHe8, CLOCK, BHLHE8, KIAA0334, clock circadian regulator
Background: Biological timepieces called circadian clocks are responsible for the regulation of hormonal rhythms, sleep cycles and other behaviors. The superchiasmatic nucleus (SCN), which is located in the brain, was the first mammalian circadian clock to be discovered. Clock, a member of the Basic-helix-loop-helix-psp (bHLH-PAS) family of transcription factors, has also been identified as having circadian function. Mutations within the clock gene have been shown to increase the length of the endogenous period and To contain a loss of rhythmicity of circadian oscillations. Clock contains a DNA-binding domain, a protein dimerization domain and a glutamine-rich C-terminal region, which indicates transactivation ability. It has been speculated that Clock may regulation circadian rhythmicity in combination with Other proteins such as Per. Per is also a PAS-domain containing protein that exhibits circadian function. Highest expression of Clock is seen in the hypothalamus and the eye.
- 基因ID
- 9575
- UniProt
- O15516
- 途径
- Regulation of Lipid Metabolism by PPARalpha, Photoperiodism
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