CHAF1B 抗体
Quick Overview for CHAF1B 抗体 (ABIN6942548)
抗原
See all CHAF1B 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人
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纯化方法
- Purified by Protein A.
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免疫原
- Recombinant protein corresponding to the C-terminus of Human p60 CAF1.
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亚型
- IgG
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anti-Chromatin Assembly Factor 1, Subunit B (p60) (CHAF1B) (N-Term) antibody
CHAF1B 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, Pig, 兔, Cow, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Chromatin Assembly Factor 1, Subunit B (p60) (CHAF1B) (AA 270-559) antibodyCHAF1B 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chromatin Assembly Factor 1, Subunit B (p60) (CHAF1B) antibodyCHAF1B 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chromatin Assembly Factor 1, Subunit B (p60) (CHAF1B) (AA 1-559) antibodyCHAF1B 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Chromatin Assembly Factor 1, Subunit B (p60) (CHAF1B) (N-Term) antibodyCHAF1B 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chromatin Assembly Factor 1, Subunit B (p60) (CHAF1B) (AA 201-300) antibodyCHAF1B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G7 unconjugated
anti-Chromatin Assembly Factor 1, Subunit B (p60) (CHAF1B) antibodyCHAF1B 适用: 人, 小鼠 WB, IF, IP, ICC 宿主: 小鼠 Monoclonal 24 unconjugated
anti-Chromatin Assembly Factor 1, Subunit B (p60) (CHAF1B) antibodyCHAF1B 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Chromatin Assembly Factor 1, Subunit B (p60) (CHAF1B) (AA 1-199) antibodyCHAF1B 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chromatin Assembly Factor 1, Subunit B (p60) (CHAF1B) (AA 71-120) antibodyCHAF1B 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200
IP(1-2 μg) -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- CHAF1B (Chromatin Assembly Factor 1, Subunit B (p60) (CHAF1B))
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别名
- CHAF1B
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背景
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Synonyms: Chromatin assembly factor 1 subunit B, Chromatin assembly factor I p60 subunit, M-phase phosphoprotein 7, CAF-1 subunit B, CAF-I 60 kDa subunit, CAF-I p60, CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7, p60 CAF1
Background: Chromatin assembly factor-1 (CAF-1) is a multisubunit protein complex that comprises three polypeptide subunits known as p150, p60, and p48. CAF-1 is a nucleosome assembly factor that deposits newly synthesized and acetylated histones H3/H4 into nascent chromatin during DNA replication. The p150 subunit of CAF-1 also supports the maintenance of heterochromatin, which requires the synthesis of both new histones and heterochromatin proteins and their orderly assembly during DNA replication. Heterochromatin is characterized as densely coiled chromatin that generally replicates late during S phase, has a low gene density, and contains large blocks of repetitive DNA that is relatively inaccessible to DNA-modifying reagents. In late S phase, p150 directly associates with heterochromatin-associated proteins 1 (HP1_, HP1_ and HP1_). As cells prepare for mitosis, CAF-1 p150 and some HP1 progressively dissociate from heterochromatin, coinciding with the phosphorylation of histone H3. The HP1 proteins reassociate with chromatin at the end of mitosis, as histone H3 is dephosphorylated.
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基因ID
- 8208
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UniProt
- Q13112
抗原
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