CHAF1A 抗体 (AA 100-300)
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北京 101111
Quick Overview for CHAF1A 抗体 (AA 100-300) (ABIN6942547)
抗原
See all CHAF1A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 100-300
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原理
- CHAF1A (1D4) Monoclonal Antibody
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交叉反应
- 人
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纯化方法
- Purified by Protein A.
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免疫原
- Recombinant protein within human p150 CAF1 aa 100-300.
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亚型
- IgG
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应用备注
- WB(1:300-5000), FCM(1:20-100), IHC-P(1:200-400), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200), IP(1-2 μg)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- CHAF1A (Chromatin Assembly Factor 1, Subunit A (p150) (CHAF1A))
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别名
- CHAF1A
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背景
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Synonyms: Chromatin assembly factor 1 subunit A, Chromatin assembly factor I p150 subunit, CAF-1 subunit A, CAF-I 150 kDa subunit, CAF-I p150, hp150, p150 CAF1
Background: Core component of the CAF-1 complex, a complex thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA, histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. CHAF1A binds to histones H3 and H4. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci.
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基因ID
- 10036
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UniProt
- Q13111
抗原
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