CHAF1A 抗体
Quick Overview for CHAF1A 抗体 (ABIN6942547)
抗原
See all CHAF1A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
交叉反应
- 人
-
纯化方法
- Purified by Protein A.
-
免疫原
- Recombinant protein within human p150 CAF1 aa 100-300.
-
亚型
- IgG
-
-
-
-
应用备注
-
WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200
IP(1-2 μg) -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C for 12 months.
-
有效期
- 12 months
-
-
- CHAF1A (Chromatin Assembly Factor 1, Subunit A (p150) (CHAF1A))
-
别名
- CHAF1A
-
背景
-
Synonyms: Chromatin assembly factor 1 subunit A, Chromatin assembly factor I p150 subunit, CAF-1 subunit A, CAF-I 150 kDa subunit, CAF-I p150, hp150, p150 CAF1
Background: Core component of the CAF-1 complex, a complex thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA, histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. CHAF1A binds to histones H3 and H4. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci.
-
基因ID
- 10036
-
UniProt
- Q13111
抗原
-