CD3G 抗体
Quick Overview for CD3G 抗体 (ABIN6942433)
抗原
See all CD3G 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人, 小鼠
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纯化方法
- Purified by Protein A.
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免疫原
- Recombinant protein within C-terminal human CD3G
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亚型
- IgG
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anti-CD3g Molecule, gamma (CD3-TCR Complex) (CD3G) (AA 23-116) antibody
CD3G 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 5B7B2 unconjugated
anti-CD3g Molecule, gamma (CD3-TCR Complex) (CD3G) (AA 23-116) antibodyCD3G 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 5B7F9 unconjugated
anti-CD3g Molecule, gamma (CD3-TCR Complex) (CD3G) (AA 138-182) antibodyCD3G 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-CD3g Molecule, gamma (CD3-TCR Complex) (CD3G) (AA 48-76), (N-Term) antibodyCD3G 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD3g Molecule, gamma (CD3-TCR Complex) (CD3G) (AA 23-111) antibodyCD3G 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-CD3g Molecule, gamma (CD3-TCR Complex) (CD3G) (Internal Region) antibodyVerified CD3G 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-CD3g Molecule, gamma (CD3-TCR Complex) (CD3G) (Internal Region) antibodyCD3G 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD3g Molecule, gamma (CD3-TCR Complex) (CD3G) (Chain gamma), (N-Term) antibodyCD3G 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- CD3G (CD3g Molecule, gamma (CD3-TCR Complex) (CD3G))
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别名
- CD3G
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背景
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Synonyms: T-cell surface glycoprotein CD3 gamma chain, T-cell receptor T3 gamma chain, CD3g, CD3G, T3G
Background: Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways. In addition to this role of signal transduction in T-cell activation, CD3G plays an essential role in the dynamic regulation of TCR expression at the cell surface (PubMed:8187769). Indeed, constitutive TCR cycling is dependent on the di-leucine-based (diL) receptor-sorting motif present in CD3G.
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基因ID
- 917
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UniProt
- P09693
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途径
- TCR Signaling, CXCR4-mediated Signaling Events
抗原
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