Calsequestrin 抗体
Quick Overview for Calsequestrin 抗体 (ABIN6942360)
抗原
See all Calsequestrin (CASQ1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
交叉反应
- 人, 小鼠, 大鼠
-
纯化方法
- Purified by Protein A.
-
免疫原
- Recombinant protein within human Calsequestrin 1 aa 100-250
-
亚型
- IgG
-
-
-
-
应用备注
-
FCM 1:20-100
IHC-P 1:200-400
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
有效期
- 12 months
-
-
- Calsequestrin (CASQ1) (Calsequestrin 1 (CASQ1))
-
别名
- CASQ1
-
背景
-
Synonyms: Calsequestrin 1, Calmitine, Calsequestrin skeletal muscle isoform, CASQ1, CASQ, PDIB1, VMCQA
Background: The sarcoplasmic reticulum (SR) is, in part, responsible for maintaining the level of intracellular calcium in cardiac and skeletal muscle by storing and releasing calcium. Several intralumenal SR calcium binding proteins have been identified, the most prominent of these is calsequestrin. Calsequstrin is a calcium binding protein known to sequester calcium accumulated in the sarcoplasmic reticulum of muscle cells during relaxation and is found discretely localized to the junctional and corbular (terminal cisternae) SR. Calsequestrin functions to localize calcium near the junctional face of the terminal cisternae from which calcium can be released into the cytosol via the ryanodine receptor. This protein is highly acidic and has a large capacity and moderate to low affinity for calcium.
-
基因ID
- 844
-
UniProt
- P31415
抗原
-