Recombinant CAMK4 抗体 (C-Term)
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Quick Overview for Recombinant CAMK4 抗体 (C-Term) (ABIN6942339)
抗原
See all CAMK4 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- CAMK4 Recombinant Antibody
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交叉反应
- 人
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纯化方法
- Purified by Protein A.
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免疫原
- Recombinant protein corresponding to the C-terminus of human CAMKIV.
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亚型
- IgG
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anti-Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) (AA 1-473) antibody
CAMK4 适用: 人 WB, ELISA, IF, IHC (p), RNAi 宿主: 小鼠 Monoclonal 1A3 unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) (AA 35-292) antibodyCAMK4 适用: 人 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 8C5B8 unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) (AA 304-473) antibodyCAMK4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) (AA 19-469) antibodyCAMK4 适用: 小鼠, 大鼠 WB, IHC, ELISA, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) (AA 35-292) antibodyCAMK4 适用: 人 WB, IHC, ELISA, FACS, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) (AA 1-473) antibodyCAMK4 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) antibodyKD Validated CAMK4 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB4185 unconjugated Recombinant Antibody
anti-Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) (AA 1-473) antibodyCAMK4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) (AA 1-474) antibodyCAMK4 适用: 人 WB, IHC, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1A3 unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) (AA 304-473) antibodyCAMK4 适用: 人 WB, ELISA, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB(1:500-2000), IHC-P(1:100-200), IHC-F(1:100-200), IF(1:100-200), Flow-Cyt(1:50-100), ICC/IF(1:50-200)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- CAMK4 (Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4))
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别名
- CAMK4
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背景
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Synonyms: Calcium/calmodulin-dependent protein kinase type IV, CaM kinase-GR, CaMK IV, CAMK4, CAMK, CAMK-GR, CAMKIV
Background: Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK4 signaling cascade and regulates, mainly by phosphorylation, the activity of several transcription activators, such as CREB1, MEF2D, JUN and RORA, which play pivotal roles in immune response, inflammation, and memory consolidation. In the thymus, regulates the CD4+/CD8+ double positive thymocytes selection threshold during T-cell ontogeny. In CD4 memory T-cells, is required to link T-cell antigen receptor (TCR) signaling to the production of IL2, IFNG and IL4 (through the regulation of CREB and MEF2). Regulates the differentiation and survival phases of osteoclasts and dendritic cells (DCs). Mediates DCs survival by linking TLR4 and the regulation of temporal expression of BCL2. Phosphorylates the transcription activator CREB1 on 'Ser-133' in hippocampal neuron nuclei and contribute to memory consolidation and long term potentiation (LTP) in the hippocampus. Can activate the MAP kinases MAPK1/ERK2, MAPK8/JNK1 and MAPK14/p38 and stimulate transcription through the phosphorylation of ELK1 and ATF2. Can also phosphorylate in vitro CREBBP, PRM2, MEF2A and STMN1/OP18.
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基因ID
- 814
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UniProt
- Q16566
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途径
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Production of Molecular Mediator of Immune Response, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
抗原
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