4E-BP1/2/3 抗体 (pThr45)
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- 抗原 See all 4E-BP1/2/3 products
- 4E-BP1/2/3
- 抗原表位
- pThr45
- 适用
- 人, 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This 4E-BP1/2/3 antibody is un-conjugated
- 应用范围
- Western Blotting (WB)
- 交叉反应
- 人, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- Synthetic peptide derived from human 4E-BP1/2/3 (Thr 45), around 35-55aa.
- 克隆位点
- 3G2
- 亚型
- IgG2a
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- 应用备注
- WB 1:300-5000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- 4E-BP1/2/3
- Abstract
- 4E-BP1/2/3 产品
- 背景
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Synonyms: ABCA1 phospho S2054, p-ABCA1 phospho S2054, ATP binding cassette transporter A1, ABC 1, ABC Transporter 1, ABC1, ABCA 1, ABCA1, ATP binding Cassette 1, ATP binding cassette sub family A ABC1 member 1, ATP binding cassette sub family A member 1, ATP binding cassette sub-family A member 1, ATP binding Cassette Transporter 1, ATP-binding Cassette 1, ATP-binding Cassette Transporter 1, CERP, Cholesterol Efflux Regulatory Protein, FLJ14958, HDLDT1, Membrane bound, MGC164864, MGC165011, TD, TGD, ABCA1_HUMAN.
Background: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. In humans, this protein functions as a cholesterol efflux pump in the cellular lipid removal pathway. Mutations in the human gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency.
- 基因ID
- 19
- UniProt
- O95477
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