ADIPOQ 抗体 (AA 145-226)
Quick Overview for ADIPOQ 抗体 (AA 145-226) (ABIN6941122)
抗原
See all ADIPOQ 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 145-226
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特异性
- This MAb reacts with adiponectin, an adipocytokine. Adipocytokines are hormones produced in adipose tissue. Adiponectin is abundantly present in plasma and has insulin like effect on glucose levels in the blood. Plasma adiponectin levels are low in insulin resistant patients who are obese, have diabetes mellitus type 2 or HIV-lipodystrophy. In women adiponectin levels tend to be higher than in men, which may be due to androgens suppressing adiponectin levels. Furthermore adiponectin and leptin are both indicated in regulating body weight through direct action on the hypothalamus, influencing appetite. Obese people have low adiponectin levels while levels in anorexia patients are high. Adiponectin acts as ligand for various receptors, two of which have been identified, one probably involved in carbohydrate assimilation, the other in tuning the rate of metabolism.
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纯化方法
- Purified by Protein A/G
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免疫原
- Recombinant human Adiponectin protein fragment (around aa 145-226) (exact sequence is proprietary)
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亚型
- IgG2b kappa
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应用备注
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Positive Control: HeLa cells. Kidney.
Known Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- ADIPOQ (Adiponectin (ADIPOQ))
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别名
- ADIPOQ
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分子量
- 26-30kDa
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基因ID
- 9370
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UniProt
- Q15848
抗原
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