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CD22 抗体

This anti-CD22 antibody is a 小鼠 单克隆 antibody detecting CD22 in FACS, IF, Func 和 IM. Suitable for 人.
产品编号 ABIN6941117
发货至: 中国

Quick Overview for CD22 抗体 (ABIN6941117)

抗原

See all CD22 抗体
CD22 (CD22 Molecule (CD22))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD22 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func), Immunomicroscopy (IM)

克隆位点

FR10B4
  • 特异性

    Recognizes a protein of 130-140 kDa, identified as CD22 (also known as BL-CAM). CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types. In B-cell ontogeny, CD22 is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. It is not expressed by plasma cells, CD22 is found highly expressed in follicular mantle and marginal zone B-cells, and while germinal center B-cells are relatively weak. CD22 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation.

    纯化方法

    Purified by Protein A/G

    免疫原

    Human Burkitt's lymphoma cells

    亚型

    IgG1 kappa
  • 应用备注

    Positive Control: Raji, Daudi, IM9, JY25 and human peripheral blood lymphocytes. Human tonsil and lymphocytes.

    Known Application: Functional Studies (Order Ab without Azide), Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    CD22 (CD22 Molecule (CD22))

    别名

    CD22

    分子量

    130-140kDa

    基因ID

    933

    UniProt

    P20273
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