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CD8 alpha 抗体 (C-Term, Cytoplasmic Domain)

This anti-CD8 alpha antibody is a 兔 多克隆 antibody detecting CD8 alpha in ELISA 和 Coat. Suitable for 人.
产品编号 ABIN6941082
发货至: 中国

Quick Overview for CD8 alpha 抗体 (C-Term, Cytoplasmic Domain) (ABIN6941082)

抗原

See all CD8 alpha (CD8A) 抗体
CD8 alpha (CD8A) (CD8a Molecule (CD8A))

适用

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宿主

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克隆类型

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多克隆

标记

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This CD8 alpha antibody is un-conjugated

应用范围

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ELISA, Coating (Coat)
  • 抗原表位

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    C-Term, Cytoplasmic Domain

    免疫原

    Recombinant fragment from C-terminal cytoplasmic domain of alpha chain of human CD8 (exact sequence is proprietary).

    亚型

    IgG
  • 应用备注

    Positive Control: HuT78 or hPBL. Tonsil.

    Known Application: ELISA (For coating, order Ab without BSA), Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    200 µg/mL of antibody Purified from rabbit anti-serum by Protein A chromatography. Supplied in 10 mM PBS, pH 7.4 with 0.05 % BSA and 0.05 % sodium azide. Contact us if you require this antibody in a different format.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    CD8 alpha (CD8A) (CD8a Molecule (CD8A))

    别名

    CD8A

    背景

    CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha). A majority of thymocytes and a subpopulation of mature T cells and NK cell express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4+/CD8-. Anaplastic large cell lymphoma is usually CD4+ and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8 are often co-expressed. CD8 is also found in littoral cell angioma of the spleen.

    分子量

    32kDa

    基因ID

    925

    UniProt

    P01732

    途径

    TCR Signaling
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