RCAS1 抗体
Quick Overview for RCAS1 抗体 (ABIN6941019)
抗原
See all RCAS1 (EBAG9) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Purified by Protein A/G
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免疫原
- Recombinant human full-length EBAG9 protein
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亚型
- IgG2c kappa
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anti-Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9) (AA 1-213) antibody
EBAG9 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4A10 unconjugated
anti-Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9) (AA 31-213) antibodyEBAG9 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9) antibodyEBAG9 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal CPTC-EBAG9-2 unconjugated
anti-Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9) (C-Term) antibodyEBAG9 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9) (C-Term) antibodyVerified EBAG9 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9) (C-Term) antibodyEBAG9 适用: 人, 小鼠, 大鼠, 兔, Cow, 豚鼠, 马, 小鸡, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9) (AA 28-213) antibodyEBAG9 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9) (C-Term) antibodyEBAG9 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9) (AA 88-117) antibodyEBAG9 适用: 人 WB 宿主: 兔 Polyclonal RB41813 unconjugated
anti-Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9) (C-Term) antibodyEBAG9 适用: 人, 小鼠, 大鼠, 兔, 犬, Cow, 豚鼠, 马, Saccharomyces cerevisiae, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Positive Control: MCF-7, Jurkat, 293 cell lysates, Human skeletal muscle tissue.
Known Application: Immunofluorescence (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- RCAS1 (EBAG9) (Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9))
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别名
- EBAG9
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背景
- EBAG9, also known as RCAS1, is an estrogen-transcribed protein. Soluble and membranous RCAS1 proteins may play a role in the immune escape of tumor cells by promoting T lymphocyte inhibition of growth and apoptosis. RCAS1 is expressed in a wide variety of cancers, including uterine, ovarian, and lung cancer cells, and acts as a ligand for a putative receptor present on peripheral lymphocytes. RCAS1 is highly expressed not only in cancer cells but also in non-tumor bile duct cells subject to immune attack. RCAS1 inhibits the in vitro growth of receptor-expressing cells and induces apoptosis, contributing to the ability of tumor cells to evade host immune surveillance. High expression of RCAS1 significantly correlates with tumor progression and with poor outcome for many cancer patients.
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分子量
- 32kDa
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基因ID
- 9166
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UniProt
- O00559
抗原
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