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ACTN2 抗体 (AA 557-692)

This anti-ACTN2 antibody is a 小鼠 单克隆 antibody detecting ACTN2 in WB, IHC 和 StM. Suitable for 人.
产品编号 ABIN6940979
发货至: 中国

Quick Overview for ACTN2 抗体 (AA 557-692) (ABIN6940979)

抗原

See all ACTN2 抗体
ACTN2 (Actinin, alpha 2 (ACTN2))

适用

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宿主

  • 81
  • 61
小鼠

克隆类型

  • 74
  • 68
单克隆

标记

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This ACTN2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Staining Methods (StM)

克隆位点

ACTN2-3292
  • 抗原表位

    • 56
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    • 2
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    • 1
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    AA 557-692

    纯化方法

    Purified by Protein A/G

    免疫原

    A recombinant fragment (aa557-692) of human ACTN2 protein (exact sequence is proprietary)

    亚型

    IgG2b kappa
  • 应用备注

    Positive Control: Skeletal or Cardiac Muscle.

    Known Application: Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    ACTN2 (Actinin, alpha 2 (ACTN2))

    别名

    ACTN2

    背景

    Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In non-muscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.

    分子量

    103kDa

    基因ID

    88

    UniProt

    P35609

    途径

    Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Negative Regulation of Transporter Activity
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