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PDCD1LG2 抗体 (AA 27-220)

The 小鼠 单克隆 anti-PDCD1LG2 antibody (Clone PDL2-2676) (ABIN6940946) specifically detects PDCD1LG2 in WB, FACS, ELISA, IF 和 Coat. The antibody is reactive with 人 samples.
产品编号 ABIN6940946
发货至: 中国
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Quick Overview for PDCD1LG2 抗体 (AA 27-220) (ABIN6940946)

抗原

See all PDCD1LG2 抗体
PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))

适用

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宿主

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小鼠

克隆类型

  • 86
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单克隆

标记

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This PDCD1LG2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunofluorescence (IF), Coating (Coat)

克隆位点

PDL2-2676
  • 抗原表位

    • 22
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    AA 27-220

    特异性

    Recognizes a protein of about 31 kDa, which is identified as PD-L2 (same as PDCD1LG2). Engagement of CD28 by B7-1 (CD80) or B7-2 (CD86) in the presence of antigen promotes T cell proliferation, cytokine production, differentiation of effector T cells and the induction of Bcl-x, a promoter of T cell survival. Conversely, engagement of CTLA4 by B7-1 or B7-2 may inhibit proliferation and IL-2 production. PD-L2 does not bind CD28, cytotoxic T lymphocyte A4 or ICOS (inducible co-stimulator). The constitutive expression of PD-L1 and PD-L2 on parenchymal cells of heart, lung and kidney suggests that the Pdcd-1-Pdcd-L system could provide unique negative signaling to help prevent autoimmune disease.

    纯化方法

    Purified by Protein A/G

    免疫原

    Recombinant fragment (around aa 27-220) of human PD-L2 protein (exact sequence is proprietary)

    亚型

    IgG1 kappa
  • 应用备注

    Positive Control: Jurakt, HepG2, THP-1, RAW, NIH3T3, U87 cells Placenta or Pancreas. Thyroid Carcinoma.

    Known Application: ELISA (For coating, order antibody without BSA),Flow Cytometry (1-2 μg/million cells),Immunofluorescence (1-2 μg/mL),Western Blot (1-2 μg/mL),Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))

    别名

    PDCD1LG2

    分子量

    31kDa

    基因ID

    80380
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