VTCN1 抗体
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北京 101111
Quick Overview for VTCN1 抗体 (ABIN6940936)
抗原
See all VTCN1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Purified by Protein A/G
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免疫原
- A recombinant fragment of human B7-H4 protein (exact sequence is proprietary)
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亚型
- IgG2a kappa
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anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 50-100) antibody
VTCN1 适用: 人 FACS, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 34-147) antibodyVTCN1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 153-241) antibodyVTCN1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (Internal Region) antibodyVerified VTCN1 适用: 人 WB, FACS, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) antibodyVTCN1 适用: 人 IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal H74 unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) antibodyVTCN1 适用: 人 IHC, FACS, ELISA, IF, Coat, StM 宿主: 兔 Monoclonal B7H4-2652R unconjugated Recombinant Antibody
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 25-259) antibodyVTCN1 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 3A9C12 unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 26-258) antibodyVTCN1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) (AA 34-147) antibodyVTCN1 适用: 人 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal 6# unconjugated
anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) antibodyVTCN1 适用: 人 FACS 宿主: 兔 Chimeric unconjugated Fc fragment
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应用备注
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Positive Control: HCT116, HeLa, SKBr-3, MCF-7 cells. Ovary, Pancreas, Placenta or Spleen.
Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Flow Cytometry (1-2 μg/million cells in 0.1ml), ,Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- VTCN1 (V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1))
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别名
- VTCN1
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背景
- T cell activation and immune function are regulated by the innate immune system through positive and negative costimulatory proteins. One such protein, B7-H4 (B7-homolog 4), belongs to the B7 immunoglobulin superfamily of ligand-lymphocyte interacting proteins. Expressed primarily on the membrane of lymphoid cells, B7-H4 is an immuno-inhibitory protein that interacts with receptors on the surface of T lymphocytes, thus mediating cellular and humoral immune responses. Overexpression of the B7-H4 protein is associated with certain malignancies, including ovarian and breast cancer, as its interaction with T cells suppresses tumor-associated immunity. Current research suggests that, similar to Mucin 16 (CA-125), B7-H4 may be a useful biomarker for the early detection of ovarian cancer.
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分子量
- 35kDa
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基因ID
- 79679
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UniProt
- Q7Z7D3
抗原
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