电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

PAX8 抗体 (AA 60-261)

This anti-PAX8 antibody is a Mouse Monoclonal antibody detecting PAX8 in WB, IHC, StM. Suitable for Human.
产品编号 ABIN6940923
发货至: 中国

Quick Overview for PAX8 抗体 (AA 60-261) (ABIN6940923)

抗原

See all PAX8 抗体
PAX8 (Paired Box 8 (PAX8))

适用

  • 117
  • 49
  • 42
  • 20
  • 20
  • 7
  • 6
  • 5
  • 4
  • 2
  • 2
  • 1

宿主

  • 81
  • 37
  • 1
小鼠

克隆类型

  • 62
  • 57
单克隆

标记

  • 66
  • 8
  • 6
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PAX8 antibody is un-conjugated

应用范围

  • 89
  • 39
  • 35
  • 31
  • 28
  • 19
  • 14
  • 12
  • 11
  • 10
  • 6
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Staining Methods (StM)

克隆位点

PAX8-1491
  • 抗原表位

    • 27
    • 9
    • 9
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 60-261

    特异性

    Recognizes a protein of 62 kDa, identified as PAX8. It is a member of the paired box (PAX) family of transcription factors. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas, and atypical thyroid adenomas. PAX-8 is expressed in the thyroid (and associated carcinomas), non-ciliated mucosal cells of the fallopian tubes, and simple ovarian inclusion cysts, but not normal ovarian surface epithelial cells. PAX-8 is expressed in a high percentage of ovarian serous, endometrioid, and clear cell carcinomas, but only rarely in primary ovarian mucinous adenocarcinomas. PAX-8 expression is reported in renal tubules as well as renal cell carcinoma, nephroblastoma, and seminoma. PAX-8 antibody may be used as an additional immunohistochemical marker for renal epithelial tumors.

    纯化方法

    Purified by Protein A/G

    免疫原

    Recombinant fragment (around aa 60-261) of human PAX8 protein (exact sequence is proprietary)

    亚型

    IgG2b kappa
  • 应用备注

    Positive Control: Raji cells. Renal Cell Carcinoma (RCC).

    Known Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    PAX8 (Paired Box 8 (PAX8))

    别名

    PAX8

    分子量

    62kDa

    基因ID

    7849

    UniProt

    Q06710

    途径

    Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Stem Cell Maintenance, Tube Formation
You are here:
Chat with us!