Recombinant WT1 抗体
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- 抗原 See all WT1 抗体
- WT1 (Wilms Tumor 1 (WT1))
- 抗体类型
- Recombinant Antibody
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适用
- 人
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This WT1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Staining Methods (StM)
- 特异性
- Recognizes a 47-55 kDa-tumor suppressor protein, identified as Wilm's Tumor (WT1) protein. The antibody reacts with all isoforms of the full-length WT1 and also identifies WT1 lacking exon 2-encoded amino acids, frequently found in subsets of sporadic Wilm's tumors.WT1, a sporadic and familial pediatric kidney tumor, is genetically heterogeneous. Wilm's tumor is associated with mutations of WT1, a zinc-finger transcription factor that is essential for the development of the metanephric kidney and the urogenital system. The WT1 gene is normally expressed in fetal kidney and mesothelium, and its expression has been suggested as a marker for Wilm's tumor and mesothelioma. WT1 protein has been identified in proliferative mesothelial cells, malignant mesothelioma, ovarian carcinoma, gonadoblastoma, nephroblastoma, and desmoplastic small round cell tumor. Lung adenocarcinomas rarely stain positive with this antibody. WT1 protein expression in mesothelial cells has become a reliable marker for the diagnosis of mesotheliomas.
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Recombinant human full-length WT1 protein
- 克隆位点
- WT1-1434R
- 亚型
- IgG
- Top Product
- Discover our top product WT1 Primary Antibody
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anti-Wilms Tumor 1 (WT1) (AA 1-302) antibody
WT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Wilms Tumor 1 (WT1) (AA 1-181) antibodyWT1 适用: 人, 猴 FACS, IHC, WB, ELISA, ICC 宿主: 小鼠 Monoclonal 7F9E8 unconjugated
anti-Wilms Tumor 1 (WT1) antibodyWT1 适用: 人, 小鼠, 大鼠 IHC, StM 宿主: 小鼠 Monoclonal rWT1-857 unconjugated Recombinant Antibody
anti-Wilms Tumor 1 (WT1) (AA 1-181) antibodyWT1 适用: 人, 猴 FACS, WB, ELISA 宿主: 小鼠 Monoclonal 7F9G7H2 unconjugated
anti-Wilms Tumor 1 (WT1) (C-Term) antibodyWT1 适用: 人, 小鼠, 大鼠, 兔, 犬, 猴, Bat, 小鸡, 非洲爪蟾 IHC, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Wilms Tumor 1 (WT1) (AA 1-181) antibodyWT1 适用: 人, 小鼠, 大鼠 IHC, StM 宿主: 小鼠 Monoclonal 6F-H2 unconjugated
anti-Wilms Tumor 1 (WT1) antibodyWT1 适用: 人 IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal WT1-857 unconjugated
anti-Wilms Tumor 1 (WT1) (AA 1-302) antibodyWT1 适用: 人 IF, WB 宿主: 兔 Polyclonal unconjugated
anti-Wilms Tumor 1 (WT1) (AA 314-479) antibodyWT1 适用: 人 FACS, WB, ELISA 宿主: 小鼠 Monoclonal 5G11A5 unconjugated
anti-Wilms Tumor 1 (WT1) (AA 346-375) antibodyWT1 适用: 人, 小鼠 IF, FACS, WB, IHC (p) 宿主: 兔 Polyclonal RB18841 unconjugated
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- 应用备注
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Positive Control: K562 cells. Wilm's Tumor, mesothelioma or fetal kidney.
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- WT1 (Wilms Tumor 1 (WT1))
- 别名
- WT1 (WT1 产品)
- 别名
- AWT1 antibody, EWS-WT1 antibody, GUD antibody, NPHS4 antibody, WAGR antibody, WIT-2 antibody, WT33 antibody, CWT1 antibody, WT1 antibody, XWT1a antibody, wt-1 antibody, wt1 antibody, xWT1 antibody, WT-1 antibody, gud antibody, wagr antibody, wt33 antibody, xwt1 antibody, wit-2 antibody, si:ch211-160j6.3 antibody, zgc:152697 antibody, D630046I19Rik antibody, Wt-1 antibody, XWT1b antibody, XeWT1 antibody, Wilms tumor 1 antibody, Wilms tumor 1 S homeolog antibody, wilms tumor 1b antibody, Wilms tumor protein antibody, Wilms tumor 1 homolog antibody, Wilms tumor 1 L homeolog antibody, WT1 antibody, wt1.S antibody, wt1 antibody, wt1b antibody, Wt1 antibody, wt1.L antibody
- 分子量
- 47-55kDa
- 基因ID
- 7490
- UniProt
- P19544
- 途径
- Tube Formation
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