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- 抗原 See all TSH receptor (TSHR) 抗体
- TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TSH receptor antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Staining Methods (StM)
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Recombinant human TSHR, B-Chain protein
- 克隆位点
- SPM222
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product TSHR Primary Antibody
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anti-Thyroid Stimulating Hormone Receptor (TSHR) (AA 21-253) antibody
TSHR 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Stimulating Hormone Receptor (TSHR) (AA 501-600) antibodyTSHR 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Stimulating Hormone Receptor (TSHR) antibodyTSHR 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Stimulating Hormone Receptor (TSHR) (AA 201-300) antibodyTSHR 适用: 人, 小鼠 ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Stimulating Hormone Receptor (TSHR) (AA 648-740) antibodyTSHR 适用: 人, 小鼠 ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Stimulating Hormone Receptor (TSHR) (AA 28-245) antibodyTSHR 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Stimulating Hormone Receptor (TSHR) antibodyTSHR 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Stimulating Hormone Receptor (TSHR) (N-Term) antibodyTSHR 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Stimulating Hormone Receptor (TSHR) antibodyTSHR 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal TSHRB-1405 unconjugated
anti-Thyroid Stimulating Hormone Receptor (TSHR) antibodyTSHR 适用: 人 ELISA, IHC, StM, Coat 宿主: 小鼠 Monoclonal TSHRA-1402 unconjugated
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- 应用备注
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Positive Control: 293T cells. Thyroid gland.
Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris buffer with 1 mM EDTA, pH 8.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))
- 别名
- TSHR (TSHR 产品)
- 别名
- CHNG1 antibody, LGR3 antibody, hTSHR-I antibody, AI481368 antibody, hypothroid antibody, hyt antibody, pet antibody, TSHRA antibody, TSH-R antibody, thyroid stimulating hormone receptor antibody, tshr antibody, TSHR antibody, Tshr antibody
- 背景
- Thyroid-stimulating hormone (TSH, also known as thyrotropin) is a glycoprotein involved in the control of thyroid structure and metabolism, which stimulates the release of the thyroid hormones. TSH is regulated by thyroid hormone (T3) and various retinoid compounds. TSH binds to the thyroid-stimulating hormone receptor (TSHR), which is cleaved into two subunits, A and B, and plays a major role in regulating thyroid function. The third cytoplasmic loop of TSHR has been identified as critical for its role in regulating inositol phosphate and cAMP formation. In Grave's disease, an autoimmune disorder, TSHR is activated by autoantibodies, which may be stimulated by the cleavage of the A and B subunits.
- 分子量
- 42kDa
- 基因ID
- 7253
- UniProt
- P16473
- 途径
- Thyroid Hormone Synthesis
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