Tumor Protein p73 抗体
Quick Overview for Tumor Protein p73 抗体 (ABIN6940795)
抗原
See all Tumor Protein p73 (TP73) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
 - Purified by Protein A/G
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免疫原
 - Recombinant full-length human TP73 protein
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亚型
 - IgG2b kappa
 
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应用备注
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Positive Control: HeLa, Jurkat, HEK293 cell lysates. Human kidney or bladder carcinoma.
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
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限制
 - 仅限研究用
 
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浓度
 - 200 μg/mL
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缓冲液
 - 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - 4 °C,-80 °C
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储存方法
 - Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
 - 24 months
 
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- Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))
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别名
 - TP73
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背景
 - The p53 gene is a widely studied anti-oncogene, or tumor suppressor gene. The p53 gene product can act as a negative regulator of cell growth in response to DNA damage. Mutations and allelic loss of the p53 gene have been associated with malignant transformation in a wide variety of human tumors. p53 shares considerable sequence similarity with p73, a gene that maps to a region in chromosome 1 that is frequently deleted in neuroblastomas. However, p73 does not appear to be activated by DNA damaging agents. The p73 isoform p73.
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分子量
 - 73kDa
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基因ID
 - 7161
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UniProt
 - O15350
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途径
 - Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus
 
抗原
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