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TIMP3 抗体 (AA 175-211)

This anti-TIMP3 antibody is a 兔 多克隆 antibody detecting TIMP3 in IHC, FACS, IF 和 StM. Suitable for 人, 小鼠, 大鼠, Cow, 犬 和 马.
产品编号 ABIN6940740
发货至: 中国

Quick Overview for TIMP3 抗体 (AA 175-211) (ABIN6940740)

抗原

See all TIMP3 抗体
TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

适用

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人, 小鼠, 大鼠, Cow, 犬, 马

宿主

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克隆类型

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多克隆

标记

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This TIMP3 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Staining Methods (StM)
  • 抗原表位

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    AA 175-211

    免疫原

    The amino acid sequence (aa175-211), used as the immunogen for TIMP3 Ab, is 100% homologous in human, cow, dog and horse, and 94% homologous in Mouse and rat.

    亚型

    IgG
  • 应用备注

    Positive Control: Placenta or breast carcinoma.

    Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

    别名

    TIMP3

    背景

    TIMP3 (tissue inhibitor of metalloproteinases 3), along with family members TIMP1, TIMP2, and TIMP4, are inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix (ECM). An imbalance between MMPs and the associated TIMPs may play a significant role in the invasive phenotype of malignant tumors. TIMP's inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes.

    分子量

    30kDa

    基因ID

    7078

    UniProt

    P35625
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