Recombinant Thyroglobulin 抗体
Quick Overview for Recombinant Thyroglobulin 抗体 (ABIN6940703)
抗原
See all Thyroglobulin (TG) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- MAb r2H11 reacts with a partially defined epitope of human thyroglobulin. This epitope is different form the epitope recognized by MAb 6E1. Thyroglobulin is a 660 kDa dimeric pre-protein with mutiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable marker to differentiate between primary thyroid and lung neoplasms.
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纯化方法
- Purified by Protein A/G
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免疫原
- Human thyroid follicular cells
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亚型
- IgG1 kappa
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anti-Thyroglobulin (TG) (AA 2659-2768) antibody
TG 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 1G3 unconjugated
anti-Thyroglobulin (TG) antibodyTG 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal r6E1 unconjugated Recombinant Antibody
anti-Thyroglobulin (TG) antibodyTG 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-189R unconjugated Recombinant Antibody
anti-Thyroglobulin (TG) (AA 2083-2333) antibodyTG 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thyroglobulin (TG) antibodyTG 适用: 人, Cow IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Thyroglobulin (TG) antibodyTG 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Thyroglobulin (TG) antibodyTG 适用: 人 IHC, StM 宿主: 兔 Monoclonal TGB-1970R unconjugated Recombinant Antibody
anti-Thyroglobulin (TG) antibodyTG 适用: 人 IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Thyroglobulin (TG) (C-Term) antibodyTG 适用: 人 IHC (p) 宿主: 兔 Monoclonal E23-Y unconjugated
anti-Thyroglobulin (TG) (C-Term) antibodyTG 适用: 人 IHC (p) 宿主: 兔 Monoclonal E23-Y unconjugated
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应用备注
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Positive Control: Thyroid.
Known Application: Immunohistochemistry (Formalin-fixed) (0.1-0.2 μg/mL, 30 min at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- Thyroglobulin (TG)
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别名
- Thyroglobulin (Thyroidal Cell Marker)
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分子量
- 660kDa (Dimeric Form)
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基因ID
- 7038
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UniProt
- P01266
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途径
- Thyroid Hormone Synthesis
抗原
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