HNF1A 抗体 (AA 214-339)
Quick Overview for HNF1A 抗体 (AA 214-339) (ABIN6940684)
抗原
See all HNF1A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 214-339
-
纯化方法
- Purified by Protein A/G
-
免疫原
- Recombinant fragment (around aa 214-339) of human HNF1A protein (exact sequence is proprietary)
-
亚型
- IgG1 kappa
-
-
-
-
应用备注
-
Positive Control: Jurkat cells. Small Intestine or Pancreas.
Known Application: ELISA (For coating, order antibody without BSA),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
-
限制
- 仅限研究用
-
-
-
浓度
- 200 μg/mL
-
缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-80 °C
-
储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
-
有效期
- 24 months
-
-
- HNF1A (HNF1 Homeobox A (HNF1A))
-
别名
- HNF1A
-
背景
- HNF1A belongs to the homeobox protein family and is an essential transcription factor for many hepatic genes involved in detoxification, homeostasis and metabolisms of glucose, lipid, steroid and amino acid. In addition, HNF1A is an important component of the transcriptional networks governing embryonic pancreas development and differentiation. as well as maintaining the growth and function of islet cells in adult. HNF1A (Hepatocyte nuclear factor 1 alpha) is a transcription factor that is known to regulate pancreatic differentiation and maintain homeostasis of endocrine pancreas. Recently, genome-wide association studies have implicatedHNF1Aas a susceptibility gene for pancreatic cancer.
-
分子量
- 79kDa
-
基因ID
- 6927
-
UniProt
- P20823
-
途径
- Hormone Transport, Carbohydrate Homeostasis
抗原
-