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TAL1 抗体

TAL1 适用: 人 WB, ELISA, Coat 宿主: 小鼠 Monoclonal BTL73 unconjugated
产品编号 ABIN6940681
发货至: 中国
  • 抗原 See all TAL1 抗体
    TAL1 (T-Cell Acute Lymphocytic Leukemia 1 (TAL1))
    适用
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    宿主
    • 84
    • 6
    小鼠
    克隆类型
    • 85
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    单克隆
    标记
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    This TAL1 antibody is un-conjugated
    应用范围
    • 64
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    Western Blotting (WB), ELISA, Coating (Coat)
    纯化方法
    Purified by Protein A/G
    免疫原
    Recombinant human full-length TAL1 protein
    克隆位点
    BTL73
    亚型
    IgG1 kappa
    Top Product
    Discover our top product TAL1 Primary Antibody
  • 应用备注

    Positive Control: A549 xenograft.

    Known Application: ELISA (For coating, order antibody without BSA), Western Blot (0.5-1.0 μg/mL), Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    TAL1 (T-Cell Acute Lymphocytic Leukemia 1 (TAL1))
    别名
    TAL1 (TAL1 产品)
    别名
    SCL/tal-1 antibody, Scl antibody, bHLHa17 antibody, tal-1 antibody, SCL antibody, TCL5 antibody, scl antibody, tcl5 antibody, SCL-alpha antibody, SCL-beta antibody, scl/tal1 antibody, zgc:85605 antibody, T cell acute lymphocytic leukemia 1 antibody, TAL bHLH transcription factor 1, erythroid differentiation factor antibody, T-cell acute lymphocytic leukemia 1 S homeolog antibody, T-cell acute lymphocytic leukemia 1 antibody, Tal1 antibody, TAL1 antibody, tal1.S antibody, tal1 antibody
    背景
    Activation of TAL1 characterizes up to 60 % of cases of human T cell acute lymphoblastic leukemia, making it the most frequent gain-of-function mutation observed in this disorder. TAL1 (also designated SCL) is a serine phosphoprotein and basic helix-loop-helix transcription factor known to regulate embryonic hematopoiesis. This transcription factor binds as a heterodimer with E2A and HEB/HTF4 to a nucleotide sequence motif termed the E-box. In addition, leukemogenesis is accelerated dramatically by transgenic co-expression of TAL1 and the catalytic subunit of casein kinase IIHLH transcription factors.
    分子量
    42kDa
    基因ID
    6886
    UniProt
    P17542
    途径
    Stem Cell Maintenance
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