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TAL1 抗体

This anti-TAL1 antibody is a 小鼠 单克隆 antibody detecting TAL1 in ELISA 和 Coat. Suitable for 人.
产品编号 ABIN6940680
发货至: 中国

Quick Overview for TAL1 抗体 (ABIN6940680)

抗原

See all TAL1 抗体
TAL1 (T-Cell Acute Lymphocytic Leukemia 1 (TAL1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This TAL1 antibody is un-conjugated

应用范围

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ELISA, Coating (Coat)

克隆位点

TAL1-2707
  • 纯化方法

    Purified by Protein A/G

    免疫原

    Recombinant human full-length TAL1 protein

    亚型

    IgG2a kappa
  • 应用备注

    Positive Control: A549 xenograft.

    Known Application: ELISA (For coating, order antibody without BSA), Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    TAL1 (T-Cell Acute Lymphocytic Leukemia 1 (TAL1))

    别名

    TAL1

    背景

    Activation of TAL1 characterizes up to 60 % of cases of human T cell acute lymphoblastic leukemia, making it the most frequent gain-of-function mutation observed in this disorder. TAL1 (also designated SCL) is a serine phosphoprotein and basic helix-loop-helix transcription factor known to regulate embryonic hematopoiesis. This transcription factor binds as a heterodimer with E2A and HEB/HTF4 to a nucleotide sequence motif termed the E-box. In addition, leukemogenesis is accelerated dramatically by transgenic co-expression of TAL1 and the catalytic subunit of casein kinase IIHLH transcription factors.

    分子量

    42kDa

    基因ID

    6886

    UniProt

    P17542

    途径

    Stem Cell Maintenance
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