Transgelin 抗体
Quick Overview for Transgelin 抗体 (ABIN6940678)
抗原
See all Transgelin (TAGLN) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This MAb recognizes a 22 kDa protein, identified as Transgelin, also designated SM22-alpha. It may cross-react with SM22-beta. Transgelin is expressed abundantly in smooth muscle cells. The human transgelin gene encodes a 201 amino acid protein that contains nuclear factor-binding motifs known to regulate transcription in smooth muscle. During embryogenesis, transgelin is expressed in smooth, cardiac and skeletal muscle, but is restricted during late fetal development and adulthood to all vascular and visceral smooth muscle cells and low levels of expression in heart. Transgelin is down regulated in several transformed cell lines, indicating that a reduction of transgelin expression may be an early indicator of the onset of transformation. Transgelin also binds Actin, causing Actin fibers to gel within minutes of binding. Binding of transgelin to Actin occurs at a ratio of 1:6 Actin monomers.
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纯化方法
- Purified by Protein A/G
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免疫原
- Recombinant full-length human transgelin (TAGLN) protein.
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亚型
- IgG1 kappa
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anti-Transgelin (TAGLN) (C-Term) antibody
Verified TAGLN 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Transgelin (TAGLN) (AA 1-201) antibodyTAGLN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transgelin (TAGLN) antibodyTAGLN 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transgelin (TAGLN) antibodyKO Validated TAGLN 适用: 人 WB, IF, IHC (p), IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transgelin (TAGLN) (AA 1-201) antibodyTAGLN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E2 unconjugated
anti-Transgelin (TAGLN) (AA 2-201) antibodyTAGLN 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transgelin (TAGLN) (AA 19-112) antibodyTAGLN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C4 unconjugated
anti-Transgelin (TAGLN) (AA 1-201) antibodyTAGLN 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3A3 unconjugated
anti-Transgelin (TAGLN) (AA 24-51), (N-Term) antibodyTAGLN 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19881 unconjugated
anti-Transgelin (TAGLN) (C-Term) antibodyTAGLN 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Positive Control: U-2 OS, Hs68 or WI 38 cells. Colon carcinoma.
Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- Transgelin (TAGLN)
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别名
- TAGLN
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分子量
- 22kDa
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基因ID
- 6876
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UniProt
- Q01995
抗原
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