CD147 抗体
Quick Overview for CD147 抗体 (ABIN6940675)
抗原
See all CD147 (BSG) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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免疫原
- Native human leucocytes
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亚型
- IgM kappa
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应用备注
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Positive Control: HSB2 cells. Renal Cell, Ovarian carcinoma or Melanoma.
Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- CD147 (BSG) (Basigin (Ok Blood Group) (BSG))
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别名
- BSG
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背景
- CD147 is a transmembrane glycoprotein of the immunoglobulin superfamily. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is involved in the regulation of matrix remodeling at the epidermal-dermal interface. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes, which are typically increased during tissue degradation and wound healing, are important factors in cancer invasion and metastasis.
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分子量
- 35kDa (non-reduced), 40kDa (reduced)
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基因ID
- 682
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UniProt
- P35613
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途径
- S100 Proteins
抗原
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