STAR 抗体 (AA 39-108)
Quick Overview for STAR 抗体 (AA 39-108) (ABIN6940666)
抗原
See all STAR 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 39-108
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纯化方法
- Purified by Protein A/G
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免疫原
- Recombinant fragment (around aa 39-108) of human STAR protein (exact sequence is proprietary)
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亚型
- IgG2b kappa
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应用备注
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Positive Control: K-562 cells. Adrenal or Testicular Carcinoma.
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- STAR (Steroidogenic Acute Regulatory Protein (STAR))
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别名
- STAR
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背景
- Steroidogenic Acute Regulatory Protein (STAR) controls the rate-limiting step of steroidegenesis by translocating cholesterol from the outer mitochondrial membrane to the inner membrane where it is later cleaved to pregnenolone.It is primarily present in steroid-producing cells, including Leydig cells in the testis, theca cells and luteal cells in the ovary and adrenal cells in the adrenal cortex. Due to low levels of pregnenolone, seminomas and Leydig cell tumors display no specific STAR staining. Therefore, STAR antibody may assist in differentiating sex cord stromal tumors (SCST), seminomas and embryonal carcinomas.
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分子量
- 30kDa
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基因ID
- 6770
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UniProt
- P49675
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途径
- Metabolism of Steroid Hormones and Vitamin D, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis
抗原
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