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SELPLG 抗体

This anti-SELPLG antibody is a 小鼠 单克隆 antibody detecting SELPLG in IHC 和 StM. Suitable for 人.
产品编号 ABIN6940571
发货至: 中国

Quick Overview for SELPLG 抗体 (ABIN6940571)

抗原

See all SELPLG 抗体
SELPLG (Selectin P Ligand (SELPLG))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This SELPLG antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Staining Methods (StM)

克隆位点

PSGL1-1601
  • 纯化方法

    Purified by Protein A/G

    免疫原

    Recombinant human SELPLG (CD162) protein

    亚型

    IgG1 kappa
  • 应用备注

    Positive Control: Jurkat cells. Tonsil or Spleen.

    Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    SELPLG (Selectin P Ligand (SELPLG))

    别名

    SELPLG

    背景

    CD162 glycoprotein functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response.

    分子量

    43-120kDa

    基因ID

    6404

    UniProt

    Q14242
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