电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

S100A9 抗体

This anti-S100A9 antibody is a 小鼠 单克隆 antibody detecting S100A9 in IHC, IF, FACS 和 StM. Suitable for 人 和 大鼠.
产品编号 ABIN6940553
发货至: 中国

Quick Overview for S100A9 抗体 (ABIN6940553)

抗原

See all S100A9 抗体
S100A9 (S100 Calcium Binding Protein A9 (S100A9))

适用

  • 137
  • 26
  • 24
  • 7
  • 3
  • 2
  • 1
  • 1
  • 1
人, 大鼠

宿主

  • 101
  • 65
  • 1
  • 1
  • 1
小鼠

克隆类型

  • 89
  • 79
  • 1
单克隆

标记

  • 84
  • 24
  • 14
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This S100A9 antibody is un-conjugated

应用范围

  • 94
  • 75
  • 42
  • 39
  • 32
  • 28
  • 24
  • 18
  • 13
  • 13
  • 9
  • 9
  • 9
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Staining Methods (StM)

克隆位点

S100A9-1075
  • 纯化方法

    Purified by Protein A/G

    免疫原

    Recombinant human S100A9 protein

    亚型

    IgG1 kappa
  • 应用备注

    Positive Control: Liver or histiocytoma.

    Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT) (For staining of formalin-fixed, paraffin-embedded tissues, digest with trypsin at 1 mg/mL PBS, 15 min at RT Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    S100A9 (S100 Calcium Binding Protein A9 (S100A9))

    别名

    S100A9

    背景

    This MAb stains the cytoplasm of macrophages and histiocytes in hematopoietic organs, Kupffers cells of the liver and Langerhans cells of the skin. It also stains the mantle zone B-lymphocytes of the lymph node and spleen, spermatogonia, and chief cells of the stomach. S100A9 is expressed by macrophages in acutely inflamed tissues and in chronic inflammation. It is detected in peripheral blood leukocytes, in neutrophils and granulocytes. It is present at sites of vascular inflammation. S100A9 is also expressed in epithelial cells constitutively or induced during dermatoses. S100A9 is a Calcium-binding protein. It has antimicrobial activity towards bacteria and fungi. It is important for resistance to invasion by pathogenic bacteria. It up-regulates transcription of genes that are under the control of NF-kappa-B. S100A9 plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide (LPS). It promotes tubulin polymerization when unphosphorylated. It also promotes phagocyte migration and infiltration of granulocytes at sites of wounding. It plays a role as a pro-inflammatory mediator in acute and chronic inflammation and up-regulates the release of IL8 and cell-surface expression of ICAM1.

    分子量

    14kDa

    基因ID

    6280

    UniProt

    P06702

    途径

    Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteins
You are here:
Chat with us!