Recombinant S100A8/A9 Complex (Calprotectin) 抗体
Quick Overview for Recombinant S100A8/A9 Complex (Calprotectin) 抗体 (ABIN6940548)
抗原
See all S100A8/A9 Complex (Calprotectin) (S100A8/A9) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes the L1 or Calprotectin molecule, an intra-cytoplasmic antigen comprising of a 12 kDa alpha chain and a 14 kDa beta chain expressed by granulocytes, monocytes and by tissue macrophages. Macrophages usually arise from hematopoietic stem cells in the bone marrow. Under migration into tissues, the monocytes undergo further differentiation to become multifunctional tissue macrophages. They are classified into normal and inflammatory macrophages. Normal macrophages include macrophages in connective tissue (histiocytes), liver (Kupffer s cells), lung (alveolar macrophages), lymph nodes (free and fixed macrophages), spleen (free and fixed macrophages), bone marrow (fixed macrophages), serous fluids (pleural and peritoneal macrophages), skin (histiocytes, Langerhans's cell) and in other tissues. Inflammatory macrophages are present in various exudates. Macrophages are part of the innate immune system, recognizing, engulfing and destroying many potential pathogens including bacteria, pathogenic protozoa, fungi and helminthes. This MAb reacts with neutrophils, monocytes, macrophages, and squamous mucosal epithelia and has been shown as an important marker for identifying macrophages in tissue sections.
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纯化方法
- Purified by Protein A/G
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免疫原
- Affinity Purified monocyte membrane preparation
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亚型
- IgG1 kappa
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anti-Calprotectin (S100A8/A9) antibody
S100A8/A9 适用: 人, Pig, Cow, Cat, 犬, 豚鼠, 猴, 兔, 大鼠, 马, Baboon, 小鼠, 山羊 IHC, StM 宿主: 兔 Monoclonal MAC3157R unconjugated Recombinant Antibody
anti-Calprotectin (S100A8/A9) antibodyAnimal-Free S100A8/A9 适用: 人 ELISA 宿主: 小鼠 Monoclonal AB467-1-A05 unconjugated Recombinant Antibody
anti-Calprotectin (S100A8/A9) antibodyS100A8/A9 适用: 人 IHC, ELISA, WB 宿主: 小鼠 Monoclonal 69-6-1 unconjugated
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应用备注
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Positive Control: Tonsil, lymph node or spleen.
Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- S100A8/A9 Complex (Calprotectin) (S100A8/A9) (Calprotectin (S100A8/A9))
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别名
- S100A8 & S100A9
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分子量
- 12-14kDa (doublet)
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基因ID
- 6279, 6280
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UniProt
- P05109, P06702
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途径
- S100 Proteins
抗原
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