RORC 抗体
Quick Overview for RORC 抗体 (ABIN6940534)
抗原
See all RORC 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This MAb recognizes a protein of 63 kDa, identified as ROR-C. Its epitope maps in between aa1-50. The nuclear orphan receptors ROR and ROR are members of the nuclear hormone receptor superfamily. Members of this family act by directly associating with DNA sequences known as hormone response elements (HREs) and typically bind DNA as either homo- or heterodimers. RORalpha and RORgamma are unique in that they bind DNA as monomers. RORalpha has multiple isoforms that share common DNA and putative ligand-binding domains, but differ in their amino terminal domains, which are generated by alternative RNA processing. RORgamma comprises a 560 amino acid protein that shares 50 % amino acid identity with RORalpha and is most highly expressed in skeletal muscle. Although these proteins are considered orphan receptors, due to a lack of defined ligands, experimental evidence has shown that melatonin may be the natural ligand for these nuclear receptors.
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纯化方法
- Purified by Protein A/G
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免疫原
- Recombinant full-length human RORC protein
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亚型
- IgG2a kappa
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anti-RAR-Related Orphan Receptor C (RORC) (AA 212-461) antibody
RORC 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-RAR-Related Orphan Receptor C (RORC) (AA 200-212) antibodyVerified RORC 适用: 人 WB, ELISA, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-RAR-Related Orphan Receptor C (RORC) (Middle Region) antibodyRORC 适用: 人, 小鼠, 大鼠, Cow, 马, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-RAR-Related Orphan Receptor C (RORC) (N-Term) antibodyRORC 适用: 人, 小鼠, 大鼠, Cow, 马, 豚鼠, 犬, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAR-Related Orphan Receptor C (RORC) (AA 412-517) antibodyRORC 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G7 unconjugated
anti-RAR-Related Orphan Receptor C (RORC) (AA 110-159) antibodyRORC 适用: 人, Cow, 马, 豚鼠, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-RAR-Related Orphan Receptor C (RORC) (AA 1-50) antibodyRORC 适用: 人, 小鼠 WB, FACS 宿主: 小鼠 Monoclonal 4G419 unconjugated
anti-RAR-Related Orphan Receptor C (RORC) (AA 1-518) antibodyRORC 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAR-Related Orphan Receptor C (RORC) (Modulating Domain) antibodyRORC 适用: 人 ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-RAR-Related Orphan Receptor C (RORC) (Ligand Binding Domain) antibodyRORC 适用: 人, 猴, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Positive Control: Human Lymphocytes. Liver or skeletal muscle tissue.
Known Application: ELISA (For coating, order Ab without BSA), Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- RORC (RAR-Related Orphan Receptor C (RORC))
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别名
- RORC
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分子量
- 63kDa
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基因ID
- 6097
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UniProt
- P51449
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途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
抗原
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