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RBP4 抗体

This anti-RBP4 antibody is a 小鼠 单克隆 antibody detecting RBP4 in IHC 和 StM. Suitable for 人, 小鼠, 大鼠, 兔, 猴, 山羊 和 Chimpanzee.
产品编号 ABIN6940482
发货至: 中国

Quick Overview for RBP4 抗体 (ABIN6940482)

抗原

See all RBP4 抗体
RBP4 (Retinol Binding Protein 4, Plasma (RBP4))

适用

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人, 小鼠, 大鼠, 兔, 猴, 山羊, Chimpanzee

宿主

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小鼠

克隆类型

  • 157
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单克隆

标记

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This RBP4 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Staining Methods (StM)

克隆位点

G4E4
  • 特异性

    This MAb recognizes an epitope within the 74-182 C-terminal sequence (11kD peptide fragment) of human serum Cellular Retinol Binding Protein 1 (CRBP 1), a single-chain glycoprotein belonging to the superfamily of hydrophobic molecule transporter proteins, which is responsible for transport of retinol (vitamin A1) from the liver to peripheral target tissues, like the eye, where it mediates the cellular uptake. CRBP 1 is synthesized by hepatic parenchymal cells where it becomes bound to its ligand retinol and is then released into the circulation, where it binds further to the protein transthyretin, to form a transporting complex, which is big enough not to be lost by filtration through the kidney glomeruli. It is detected in nearly all tissues with higher expression in adult ovary, pancreas, pituitary gland, adrenal gland, and fetal liver.

    纯化方法

    Purified by Protein A/G

    免疫原

    Retinol binding protein-1 Purified from human plasma

    亚型

    IgG1 kappa
  • 应用备注

    Positive Control: Hepatic or Ovarian Carcinoma.

    Known Application: Immunohistochemistry (Formalin-fixed) (0.1-0.2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    RBP4 (Retinol Binding Protein 4, Plasma (RBP4))

    别名

    RBP

    分子量

    21-25kDa

    基因ID

    5947, 5948, 5950

    UniProt

    P02753, P09455, P50120

    途径

    Regulatory RNA Pathways, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response
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