ENAH 抗体 (AA 485-589)
Quick Overview for ENAH 抗体 (AA 485-589) (ABIN6940390)
抗原
See all ENAH 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 485-589
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纯化方法
- Purified by Protein A/G
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免疫原
- Recombinant fragment of human MENA protein (around aa 485-589) (exact sequence is proprietary)
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亚型
- IgG2c kappa
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应用备注
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Positive Control: MCF-7 cells. Uterus.
Known Application: ELISA (For coating, order Ab without BSA),Western Blot (1-2 μg/mL)Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- ENAH (Enabled Homolog (ENAH))
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别名
- ENAH
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背景
- The Wiskott-Aldrich syndrome (WAS) is characterized by thrombocytopenia, eczema, defects in cell-mediated and humoral immunity and a propensity for lymphoproliferative diseases. The syndrome is the result of a mutation in the gene encoding a proline-rich protein termed WASP. WASP is a downstream effector of Cdc42 and has been implicated in actin polymerization and cyto- skeletal organization. Distantly related proteins, VASP (vasodilator-stimulated phosphoprotein) and Mena (for mammalian enabled protein), are involved in the regulation of cytoskeletal dynamics. Both Mena and VASP accumulate at focal adhesions. Mena is highly expressed in the developing nervous system and may be involved in growth cone motility and axon guidance.
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分子量
- 80/88/140kDa
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基因ID
- 55740
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UniProt
- Q8N8S7
抗原
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