电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Recombinant ANO1 抗体 (AA 2-101)

This anti-ANO1 antibody is a 兔 单克隆 antibody detecting ANO1 in IHC 和 StM. Suitable for 人.
产品编号 ABIN6940378
发货至: 中国

Quick Overview for Recombinant ANO1 抗体 (AA 2-101) (ABIN6940378)

抗原

See all ANO1 抗体
ANO1 (Anoctamin 1, Calcium Activated Chloride Channel (ANO1))

抗体类型

Recombinant Antibody

适用

  • 167
  • 36
  • 26
  • 6
  • 6
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1

宿主

  • 106
  • 66

克隆类型

  • 101
  • 70
  • 1
单克隆

标记

  • 67
  • 15
  • 10
  • 8
  • 8
  • 7
  • 7
  • 7
  • 7
  • 7
  • 6
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ANO1 antibody is un-conjugated

应用范围

  • 78
  • 59
  • 50
  • 45
  • 36
  • 32
  • 20
  • 16
  • 13
  • 13
  • 10
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Staining Methods (StM)

克隆位点

DG1-2564R
  • 抗原表位

    • 39
    • 15
    • 9
    • 8
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-101

    纯化方法

    Purified by Protein A/G

    免疫原

    A recombinant human DOG-1 protein fragment (around aa 2-101) (exact sequence is proprietary)

    亚型

    IgG
  • 应用备注

    Positive Control: Gastrointestinal Stromal Tumor (GIST) or testicular germ cell tumor. Melanocytes in the basal layer of the epidermis and mast cells in the dermis of normal skin.

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    ANO1 (Anoctamin 1, Calcium Activated Chloride Channel (ANO1))

    别名

    TMEM16A

    背景

    Expression of DOG-1 protein is elevated in the gastrointestinal stromal tumors (GIST's), c-kit signaling-driven mesenchymal tumors of the GI tract. DOG-1 is rarely expressed in other soft tissue tumors, which, due to appearance, may be difficult to diagnose. Immunoreactivity for DOG-1 has been reported in 97.8 percent of scorable GIST's, including all c-kit negative GIST's. Overexpression of DOG-1 has been suggested to aid in the identification of GISTs, including Platelet-Derived Growth Factor Receptor Alpha mutants that fail to express c-kit antigen. The overall sensitivity of DOG1 and c-kit in GIST's is nearly identical: 94.4 % vs. 94.7 %.

    分子量

    ~114kDa

    基因ID

    55107
You are here:
Chat with us!