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- 抗原 See all ANO1 抗体
- ANO1 (Anoctamin 1, Calcium Activated Chloride Channel (ANO1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ANO1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Staining Methods (StM)
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Recombinant human DOG-1 protein
- 克隆位点
- SPM580
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product ANO1 Primary Antibody
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anti-Anoctamin 1, Calcium Activated Chloride Channel (ANO1) (AA 151-250) antibody
ANO1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Anoctamin 1, Calcium Activated Chloride Channel (ANO1) (AA 20-239) antibodyANO1 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Anoctamin 1, Calcium Activated Chloride Channel (ANO1) (AA 1-151) antibodyANO1 适用: 人 IF, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Anoctamin 1, Calcium Activated Chloride Channel (ANO1) (AA 2-101) antibodyANO1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal DG1-1484 unconjugated
anti-Anoctamin 1, Calcium Activated Chloride Channel (ANO1) (AA 2-101) antibodyANO1 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-201M unconjugated
anti-Anoctamin 1, Calcium Activated Chloride Channel (ANO1) (Middle Region) antibodyANO1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Anoctamin 1, Calcium Activated Chloride Channel (ANO1) antibodyANO1 适用: 人, 小鼠 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Anoctamin 1, Calcium Activated Chloride Channel (ANO1) (AA 2-101) antibodyANO1 适用: 人 IHC, StM 宿主: 兔 Monoclonal DG1-2564R unconjugated Recombinant Antibody
anti-Anoctamin 1, Calcium Activated Chloride Channel (ANO1) antibodyANO1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal rDG1-447 unconjugated Recombinant Antibody
anti-Anoctamin 1, Calcium Activated Chloride Channel (ANO1) (Internal Region) antibodyANO1 适用: 人, 小鼠, 大鼠 IF, IHC, WB, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Positive Control: Gastrointestinal Stromal Tumor (GIST) or testicular germ cell tumor. Melanocytes in the basal layer of the epidermis and mast cells in the dermis of normal skin.
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- ANO1 (Anoctamin 1, Calcium Activated Chloride Channel (ANO1))
- 别名
- TMEM16A (ANO1 产品)
- 别名
- DOG1 antibody, ORAOV2 antibody, TAOS2 antibody, TMEM16A antibody, Tmem16a antibody, anoctamin 1 antibody, anoctamin 1, calcium activated chloride channel antibody, Ano1 antibody, ANO1 antibody
- 背景
- Expression of DOG-1 protein is elevated in the gastrointestinal stromal tumors (GIST's), c-kit signaling-driven mesenchymal tumors of the GI tract. DOG-1 is rarely expressed in other soft tissue tumors, which, due to appearance, may be difficult to diagnose. Immunoreactivity for DOG-1 has been reported in 97.8 percent of scorable GIST's, including all c-kit negative GIST's. Overexpression of DOG-1 has been suggested to aid in the identification of GISTs, including Platelet-Derived Growth Factor Receptor Alpha mutants that fail to express c-kit antigen. The overall sensitivity of DOG1 and c-kit in GIST's is nearly identical: 94.4 % vs. 94.7 %.
- 分子量
- ~114kDa
- 基因ID
- 55107
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