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Progesterone Receptor 抗体 (AA 483-571)

The 小鼠 单克隆 anti-Progesterone Receptor antibody (Clone PGR-2694) (ABIN6940299) specifically detects Progesterone Receptor in IHC 和 StM. The antibody is reactive with 人 samples.
产品编号 ABIN6940299
发货至: 中国
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Quick Overview for Progesterone Receptor 抗体 (AA 483-571) (ABIN6940299)

抗原

See all Progesterone Receptor (PGR) 抗体
Progesterone Receptor (PGR)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Progesterone Receptor antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Staining Methods (StM)

克隆位点

PGR-2694
  • 抗原表位

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    AA 483-571

    特异性

    This MAb is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81 kDa) and PR-B (116 kDa). Expression of PgR has been suggested to reflect a intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than estrogen receptor (ER) alone. This MAb is excellent for immunohistochemical staining of formalin-fixed tissues.

    纯化方法

    Purified by Protein A/G

    免疫原

    Recombinant fragment of human Progesterone Receptor (PGR) protein (around aa 483-571) (exact sequence is proprietary)

    亚型

    IgG1 kappa
  • 应用备注

    Positive Control: T47-D cells. Endometrial or Breast Carcinoma.

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT) (our BEST clone)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    Progesterone Receptor (PGR)

    别名

    PGR

    分子量

    PR-A (81kDa) and PR-B (116kDa).

    基因ID

    5241

    UniProt

    P06401

    途径

    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration
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