PAX7 抗体 (AA 301-505)
Quick Overview for PAX7 抗体 (AA 301-505) (ABIN6940261)
抗原
See all PAX7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 301-505
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纯化方法
- Purified by Protein A/G
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免疫原
- Recombinant fragment (aa301-505) of human PAX7 protein (exact sequence is proprietary)
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亚型
- IgG1 kappa
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应用备注
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Positive Control: Rhabdomyosarcoma (RMS) or Testicular Carcinoma.
Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris Buffer with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- PAX7 (Paired Box 7 (PAX7))
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别名
- PAX7
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背景
- The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).
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分子量
- 57kDa
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基因ID
- 5081
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UniProt
- P23759
抗原
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