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PAX6 抗体 (N-Term)

This anti-PAX6 antibody is a Mouse Monoclonal antibody detecting PAX6 in WB, IF, FACS. Suitable for Human, Mouse, Rat, Chicken.
产品编号 ABIN6940257
发货至: 中国

Quick Overview for PAX6 抗体 (N-Term) (ABIN6940257)

抗原

See all PAX6 抗体
PAX6 (Paired Box 6 (PAX6))

适用

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人, 小鼠, 大鼠, 小鸡

宿主

  • 94
  • 41
  • 1
小鼠

克隆类型

  • 80
  • 55
单克隆

标记

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This PAX6 antibody is un-conjugated

应用范围

  • 94
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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

PAX6-498
  • 抗原表位

    • 26
    • 21
    • 16
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    • 1
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    • 1
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    AA 1-300, N-Term

    特异性

    Pax genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the Pax-6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. Pax-6 is involved in other anterior segment malformations besides aniridia, such as Peters' anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The Pax-6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human Pax-6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain.

    纯化方法

    Purified by Protein A/G

    免疫原

    Recombinant fragment (N-terminus, aa 1-300) of human PAX6 protein

    亚型

    IgG1 kappa
  • 应用备注

    Positive Control: Pancreas or Cerebellum.

    Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Western Blot (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    PAX6 (Paired Box 6 (PAX6))

    别名

    PAX6

    分子量

    47kDa

    基因ID

    5080

    UniProt

    P26367

    途径

    Peptide Hormone Metabolism, Carbohydrate Homeostasis
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