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Recombinant CD207 抗体 (AA 74-213)

This 小鼠 单克隆 anti-CD207 antibody (Clone rLGRN-1821) specifically detects CD207 in WB, ELISA 和 Coat. The antibody is reactive with 人 samples.
产品编号 ABIN6940245
发货至: 中国
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Quick Overview for Recombinant CD207 抗体 (AA 74-213) (ABIN6940245)

抗原

See all CD207 抗体
CD207 (CD207 Molecule, Langerin (CD207))

抗体类型

Recombinant Antibody

适用

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宿主

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小鼠

克隆类型

  • 70
  • 54
单克隆

标记

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This CD207 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Coating (Coat)

克隆位点

RLGRN-1821
  • 抗原表位

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    AA 74-213

    纯化方法

    Purified by Protein A/G

    免疫原

    Recombinant fragment (around aa74-213) of human Langerin protein (exact sequence is proprietary)

    亚型

    IgG1 kappa
  • 应用备注

    Positive Control: HeLa or A549 cells (WB).

    Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    CD207 (CD207 Molecule, Langerin (CD207))

    别名

    CD207

    背景

    Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2+-dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG). BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein.

    分子量

    48kDa

    基因ID

    50489

    UniProt

    Q9UJ71
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