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MUC4 抗体 (AA 1730-1864)

This anti-MUC4 antibody is a 小鼠 单克隆 antibody detecting MUC4 in IHC 和 StM. Suitable for 人.
产品编号 ABIN6940125
发货至: 中国

Quick Overview for MUC4 抗体 (AA 1730-1864) (ABIN6940125)

抗原

See all MUC4 抗体
MUC4 (Mucin 4, Cell Surface Associated (MUC4))

适用

  • 67
  • 15
  • 6
  • 1

宿主

  • 37
  • 35
小鼠

克隆类型

  • 44
  • 28
单克隆

标记

  • 45
  • 7
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MUC4 antibody is un-conjugated

应用范围

  • 44
  • 37
  • 20
  • 16
  • 12
  • 10
  • 6
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Staining Methods (StM)

克隆位点

MUC4-3084
  • 抗原表位

    • 23
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1730-1864

    纯化方法

    Purified by Protein A/G

    免疫原

    Recombinant fragment (around aa 1730-1864) of human MUC4 protein (exact sequence is proprietary)

    亚型

    IgG1 kappa
  • 应用备注

    Positive Control: Stomach, Colon or esophagus.

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    MUC4 (Mucin 4, Cell Surface Associated (MUC4))

    别名

    MUC4

    背景

    The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix, are highly glycosylated proteins called mucins. These glycoproteins play important roles in the protection of the epithelial cells and have been implicated in epithelial renewal and differentiation. This gene encodes an integral membrane glycoprotein found on the cell surface, although secreted isoforms may exist. MUC-4 transcripts have been detected in normal respiratory epithelium and lung. MUC-4 is a very specific (100 % ) and sensitive (90 %) marker of lung adenocarcinomas and is negative for mesotheliomas. Reportedly, MUC-4 expression in invasive ductal carcinoma of the pancreas is an independent factor for poor prognosis.

    分子量

    235kDa

    基因ID

    4585

    UniProt

    Q99102

    途径

    Regulation of Leukocyte Mediated Immunity
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