L1CAM 抗体
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- 抗原 See all L1CAM 抗体
- L1CAM (L1 Cell Adhesion Molecule (L1CAM))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This L1CAM antibody is un-conjugated
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应用范围
- ELISA, Coating (Coat)
- 特异性
- Recognizes a cell surface protein of 220-240 kDa, identified as L1 cell adhesion molecule. The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius), 2) MASA (mental retardation, aphasia, shuffling gait, and adducted thumbs), and 3) SPG1 (spastic paraplegia). The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, and neural migration as well as in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm. This MAb is useful in the identification of primitive neuroectodermal tumors. It binds to tumors of neuroectodermal and glial origin e.g. neuroblastoma and Schwannomas. It does not bind to pediatric or adult brain.
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Homogenous suspension of 16-week human fetal brain
- 克隆位点
- UJ127
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product L1CAM Primary Antibody
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- 应用备注
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Positive Control: Neuroblastomas or Schwannomas.
Known Application: ELISA (For coating, order antibody without BSA), Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- L1CAM (L1 Cell Adhesion Molecule (L1CAM))
- 别名
- L1CAM (L1CAM 产品)
- 分子量
- 220-240kDa
- 基因ID
- 3897
- UniProt
- P32004
- 途径
- Synaptic Membrane
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