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Cytokeratin 13 抗体

This anti-Cytokeratin 13 antibody is a 小鼠 单克隆 antibody detecting Cytokeratin 13 in IHC, IF 和 StM. Suitable for 人.
产品编号 ABIN6939905
发货至: 中国

Quick Overview for Cytokeratin 13 抗体 (ABIN6939905)

抗原

See all Cytokeratin 13 (KRT13) 抗体
Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Cytokeratin 13 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Immunofluorescence (IF), Staining Methods (StM)

克隆位点

KRT13-2213
  • 纯化方法

    Purified by Protein A/G

    免疫原

    Recombinant full-length human KRT13 protein

    亚型

    IgG
  • 应用备注

    Positive Control: HeLa or A431 cells. Skin or Squamous cell carcinoma.

    Known Application: Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))

    别名

    KRT13

    背景

    Cytokeratin 13 (KRT13) is the major acidic keratin, which together with KRT4, its basic partner, is expressed in the suprabasal layers of non-cornified stratified epithelia including tongue mucosa, esophagus, anal canal epithelium, tracheal epithelium, uterine cervix, and urothelium. Defects in the KRT13 gene are a cause of white sponge nevus of cannon (WSN), a rare autosomal dominant disorder, which predominantly affects non-cornified stratified squamous epithelia and is characterized by the presence of soft, white and spongy plaques in the oral mucosa. KRT13 has been used as a marker for non-keratinized squamous epithelium. It is also expressed in various squamous metaplasia, but it is down regulated in squamous dysplasia and squamous carcinoma.

    分子量

    52kDa

    基因ID

    3860

    UniProt

    P13646
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