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Integrin beta 4 抗体

ITGB4 适用: 人 FACS, IF, BR, Bind 宿主: 小鼠 Monoclonal UM-A9 unconjugated
产品编号 ABIN6939831
发货至: 中国
  • 抗原 See all Integrin beta 4 (ITGB4) 抗体
    Integrin beta 4 (ITGB4)
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This Integrin beta 4 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Immunofluorescence (IF), Blocking Reagent (BR), Binding Studies (Bind)
    特异性
    Recognizes a protein of 205 kDa, which is identified as integrin beta-4 (ITGB4). Its epitope is localized in the extracellular domain of ITGB4 protein. Integrins are heterodimers comprised of alpha and beta subunits, that are non-covalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta-4 subunit, a receptor for the laminins. This subunit tends to associate with alpha-6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
    纯化方法
    Purified by Protein A/G
    免疫原
    Human squamous cell carcinoma (UM-SCC1)
    克隆位点
    UM-A9
    亚型
    IgG2a kappa
    Top Product
    Discover our top product ITGB4 Primary Antibody
  • 应用备注

    Positive Control: A431 cells, squamous cell carcinoma, colon or placenta.

    Known Application: Biological Blockade (Partially blocks laminin binding) (Order Ab without Azide), Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    Integrin beta 4 (ITGB4)
    别名
    ITGB4 (ITGB4 产品)
    别名
    AA407042 antibody, C230078O20 antibody, CD104 antibody, integrin subunit beta 4 antibody, integrin beta 4 antibody, ITGB4 antibody, Itgb4 antibody
    分子量
    205kDa
    基因ID
    3691
    UniProt
    P16144
    途径
    Integrin Complex
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