Recombinant IL3RA 抗体 (AA 26-171)
Quick Overview for Recombinant IL3RA 抗体 (AA 26-171) (ABIN6939784)
抗原
See all IL3RA 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 26-171
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纯化方法
- Purified by Protein A/G
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免疫原
- Recombinant fragment of human IL3RA protein (around aa 26-171) (exact sequence is proprietary)
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亚型
- IgG
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应用备注
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Positive Control: THP-1, RPMI-8226 or HDLM-2 cells. Tonsil, Lymph Node or Stomach.
Known Application: ELISA (For coating, order antibody without BSA),Immunohistochemistry (Formalin-fixed) (0.25-0.5 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0 for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
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别名
- IL3RA
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背景
- CD123 is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudo-autosomal region on chromosomes X or Y.
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分子量
- ~70kDa
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基因ID
- 3563
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UniProt
- P26951
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途径
- JAK/STAT Signaling
抗原
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