Recombinant IGHM 抗体
Quick Overview for Recombinant IGHM 抗体 (ABIN6939724)
抗原
抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes a protein of 75 kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. IgM antibody is prominent in early immune responses to most antigens. Aberrant levels are associated with immune deficiency states, hereditary deficiencies, myeloma, Waldenstrom's macroglobulinemia, chronic infection and hepatocellular disease. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin s lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
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纯化方法
- Purified by Protein A/G
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免疫原
- Recombinant human full-length IGHM protein
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亚型
- IgG1 kappa
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anti-Immunoglobulin Heavy Constant mu (IGHM) (AA 310-452) antibody
IGHM 适用: 人 IHC, WB, FACS, ELISA 宿主: 小鼠 Monoclonal 8B9D3 unconjugated
anti-Immunoglobulin Heavy Constant mu (IGHM) antibodyIGHM 适用: 人 IHC, WB 宿主: 兔 Monoclonal unconjugated
anti-Immunoglobulin Heavy Constant mu (IGHM) antibodyIGHM 适用: 人 IHC, StM, ISt 宿主: 兔 Monoclonal IGHM-3776R unconjugated Recombinant Antibody
anti-Immunoglobulin Heavy Constant mu (IGHM) antibodyIGHM 适用: 人 IHC, WB, StM, FACS, IF 宿主: 小鼠 Monoclonal IM373 unconjugated
anti-Immunoglobulin Heavy Constant mu (IGHM) (AA 45-178) antibodyIGHM 适用: 人 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Immunoglobulin Heavy Constant mu (IGHM) (AA 1-489) antibodyIGHM 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Immunoglobulin Heavy Constant mu (IGHM) antibodyIGHM 适用: 人 IHC, StM 宿主: 兔 Monoclonal IGHM-3135R unconjugated Recombinant Antibody
anti-Immunoglobulin Heavy Constant mu (IGHM) antibodyIGHM 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal rIM373 unconjugated Recombinant Antibody
anti-Immunoglobulin Heavy Constant mu (IGHM) (AA 103-131) antibodyIGHM 适用: 人 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Immunoglobulin Heavy Constant mu (IGHM) (AA 391-440) antibodyIGHM 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Positive Control: 293T, Raji or hPBL cells. Human tonsil or spleen (IHC).
Known Application: ELISA (For coating, order antibody without BSA), ,Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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