IgD 抗体
Quick Overview for IgD 抗体 (ABIN6939707)
抗原
See all IgD 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Purified by Protein A/G
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免疫原
- Full-length human IGHD protein
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亚型
- IgG1 kappa
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anti-IgD antibody
适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-IgD (AA 1-240) antibody适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-IgD antibody适用: 人 IHC 宿主: 兔 Monoclonal MSVA-701R unconjugated Recombinant Antibody
anti-IgD (AA 1-576) antibody适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-IgD (AA 111-160) antibody适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-IgD antibody (FITC)GMP Grade 适用: 人 FACS 宿主: 小鼠 Monoclonal IA6-2 FITC
anti-IgD antibody (iFluor™647)GMP Grade 适用: 人 FACS 宿主: 小鼠 Monoclonal IA6-2 iFluor™647
anti-IgD antibody (iFluor™700)GMP Grade 适用: 人 FACS 宿主: 小鼠 Monoclonal IA6-2 iFluor™700
anti-IgD antibody (mFluor™450)GMP Grade 适用: 人 FACS 宿主: 小鼠 Monoclonal IA6-2 mFluor™450
anti-IgD (AA 37-64) antibody适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 607CT8-4-4 unconjugated
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应用备注
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Positive Control: Human tonsil lysate, NAMALWA cell lysate, Human tonsil and lymphoid tissues.
Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 1 mM EDTA buffer, pH 7.5-8.5, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- IgD
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别名
- IGHD
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物质类
- Antibody
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背景
- Immunoglobulins are four-chain, Y-shaped, monomeric structures comprised of two identical heavy chains and two identical light chains held together through interchain disulfide bonds. The chains form two domains, the Fab (antigen binding) fragment and the Fc (constant) fragment. Immunoglobulin D (IgD) exists as a monomer with light chains. It plays a biological role as a transmembrane receptor molecule, co-expressed with IgM on the surface of mature/naive B cells. In particular, it is found on spleen B cell surfaces. Compared to IgM, IgD exists in much lower numbers and is not expressed on immature B cells. IgD surface expression on B cells is regulated in part by IL-27. In mice, the inhibition of this immunoglobulin isotype does not cause a significant change to the immune system.
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分子量
- 44-80kDa (heavy chain), 21-25kDa (kappa light chain)
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基因ID
- 3495
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UniProt
- P01880
抗原
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