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IgD 抗体

This anti-IgD antibody is a 小鼠 单克隆 antibody detecting IgD in FACS, IHC, IF 和 StM. Suitable for 人.
产品编号 ABIN6939707
发货至: 中国

Quick Overview for IgD 抗体 (ABIN6939707)

抗原

See all IgD 抗体
IgD

适用

  • 40
  • 10

宿主

  • 26
  • 14
  • 9
小鼠

克隆类型

  • 25
  • 24
单克隆

标记

  • 15
  • 5
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IgD antibody is un-conjugated

应用范围

  • 24
  • 18
  • 13
  • 13
  • 12
  • 7
  • 4
  • 3
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Staining Methods (StM)

克隆位点

IgD26
  • 纯化方法

    Purified by Protein A/G

    免疫原

    Full-length human IGHD protein

    亚型

    IgG1 kappa
  • 应用备注

    Positive Control: Human tonsil lysate, NAMALWA cell lysate, Human tonsil and lymphoid tissues.

    Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 1 mM EDTA buffer, pH 7.5-8.5, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    IgD

    别名

    IGHD

    物质类

    Antibody

    背景

    Immunoglobulins are four-chain, Y-shaped, monomeric structures comprised of two identical heavy chains and two identical light chains held together through interchain disulfide bonds. The chains form two domains, the Fab (antigen binding) fragment and the Fc (constant) fragment. Immunoglobulin D (IgD) exists as a monomer with light chains. It plays a biological role as a transmembrane receptor molecule, co-expressed with IgM on the surface of mature/naive B cells. In particular, it is found on spleen B cell surfaces. Compared to IgM, IgD exists in much lower numbers and is not expressed on immature B cells. IgD surface expression on B cells is regulated in part by IL-27. In mice, the inhibition of this immunoglobulin isotype does not cause a significant change to the immune system.

    分子量

    44-80kDa (heavy chain), 21-25kDa (kappa light chain)

    基因ID

    3495

    UniProt

    P01880
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