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IFNA1 抗体

This anti-IFNA1 antibody is a 小鼠 单克隆 antibody detecting IFNA1 in WB, FACS, IF 和 IHC (fro). Suitable for 人.
产品编号 ABIN6939689
发货至: 中国

Quick Overview for IFNA1 抗体 (ABIN6939689)

抗原

See all IFNA1 抗体
IFNA1 (Interferon, alpha 1 (IFNA1))

适用

  • 74
  • 12
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  • 1

宿主

  • 48
  • 30
  • 2
小鼠

克隆类型

  • 50
  • 30
单克隆

标记

  • 36
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  • 2
  • 2
  • 2
  • 2
  • 2
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  • 1
This IFNA1 antibody is un-conjugated

应用范围

  • 33
  • 26
  • 14
  • 12
  • 9
  • 4
  • 4
  • 3
  • 3
  • 2
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Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

Feb-48
  • 纯化方法

    Purified by Protein A/G

    免疫原

    Purified recombinant human IFN-alpha1

    亚型

    IgG1 kappa
  • 应用备注

    Positive Control: Stimulated human peripheral blood mononuclear cells.

    Known Application: Flow Cytometry (0.5-1 μg/million cells), Western Blot (1-2 μg/mL), Immunohistochemistry (frozen), Immunofluorescence (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    IFNA1 (Interferon, alpha 1 (IFNA1))

    别名

    IFNA1

    背景

    This MAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.

    分子量

    16-27kDa

    基因ID

    3439

    UniProt

    P01562

    途径

    JAK/STAT Signaling, Hepatitis C
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